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Clomiphene Citrate

 Headache. 2007 Dec 7 [Epub ahead of print]
Clomiphene Citrate for Treatment Refractory Chronic Cluster Headache. 
Rozen T.
 
Michigan Head Pain and Neurological Institute, Ann Arbor, MI, USA.
 
A treatment refractory chronic cluster headache patient is presented who became cluster-free on clomiphene citrate. The author has previously reported a SUNCT patient responding to clomiphene citrate. Hypothalamic hormonal modulation therapy with clomiphene citrate may become a new preventive choice for trigeminal autonomic cephalalgias. The possible mechanism of action of clomiphene citrate for cluster headache prevention will be discussed.
 
PMID: 18070056

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