Lithium
Therapeutic management of cluster headache with lithium carbonate.
Manzoni GC, Terzano MG, Parma M
Therapeutic effectiveness of lithium carbonate in cluster headache is
confirmed on the ground of the results in 20 patients (14 with the
episodic form, 6 with the chronic one). Outstanding findings were: a)
the early effectiveness; b) the occurrence of therapeutic effects even
with low doses; c) the negligible risk of side effects. The way
interrupting the treatment in episodic cluster headache is proposed. In
chronic cluster headache recurrence can be expected when lithium is
stopped, but in some cases it occurs after a long free interval. The
contrast is stressed between the high efficacy in all the 20 patients
with cluster headache and the complete uneffectiveness in 5 patients
affected by headaches considered as borderline between cluster headache
and migraine.
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