| The medications on this page are some of the more common ones prescribed to treat cluster headaches. This list is made available strictly for you to have options to discuss with your physician. Do not take any medicine or nutritional supplement for your headaches without discussing it with your physician first! |
Cluster Headache Medications
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Cluster Headache medications are divided into three main classes: Abortive - designed to quickly stop an individual attack; Preventative - to eliminate attacks all together or to minimize them so a sufferer can lead as close to a normal life as possible; and Transitional - designed to temporarily stop attacks until a long term preventative can take effect. |
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Abortive Medications |
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| Brand Name | Type of Drug | Composition | Comments | |
| Imitrex® | vasoconstrictor | sumatriptan succinate | Comes in tablet, nasal and injectible forms. If you don't like needles click here for a needleless injector. | |
| Amerge® | vasoconstrictor | naratriptan hydrochloride | 1mg and 2.5mg tablets | |
| Please visit the medication survey page at www.clusterheadaches.com to enter your personal experiences with medications and to view other's success with them. This is a great resource in helping decide which medications work best for cluster headaches. | Zomig® | vasoconstrictor | zolmitriptan | 2.5mg and 5mg tablets; 5mg nasal spray |
| Axert® | vasoconstrictor | almotriptan maleate | 6.25mg and 12.5mg tablets | |
| Oxygen | vasoconstrictor | oxygen | 7 to 15 liters/minute via a non-rebreathing mask for 10 to 20 minutes | |
| Click here for a comparison of all the triptan based medications. | ||||
| Cafergot / Ercaf / ergotamine | vasoconstrictor | ergotamine | Tablets / suppositories / sublingual tablets | |
| We encourage you to use the various prescription medication information websites to do your own research for info on your medications. | Dihydroergotamine (DHE 45) |
vasoconstrictor | dihydroergotamine mesylate | Injection, IV or nasal spray (Migranal) |
| Lidocaine | local anesthetic | 4.5% lidocaine | Nasal spray or drops | |
| Maxalt® | vasoconstrictor | rizatriptan benzoate | 5mg, 10mg tablets | |
| Butalbital | sedative | |||
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Need More Imitrex? If you need more Imitrex than your insurance company will provide and your doctor is willing to prescribe, you can contact GlaxoSmithKline directly. They have a division called "Reimbursement Resource Center" (the name implies you have to pay up front, but that is not the case). Call them at 1-800-745-2967 option #3, give them the information they ask for, your doctor's name & number, insurance company info, etc. and they will assign you a case worker who will contact your insurance company and hopefully get them to increase the number of doses
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Stadol NS® | synthetic opiod | butorphanol tartate | Also comes in injectible form. |
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Preventative Medications |
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| Verapamil | calcium-channel blocker | verapamil hydrochloride | tablets, blood pressure medication. | |
| Catapres® | alpha-agonist | clonidine hydrochloride | tablets, blood pressure medication | |
| Lithium | anti-manic agent | lithium carbonate | Usually combined with verapamil or cortisone. Mainly for chronic clusters. Side effects. | |
| Depakote® | seizure medication | divalproex sodium | tablets | |
| Neurontin® | anticonvulsant | Gabapentin | ||
| Topamax® | antiepileptic | topiramate | Side effects | |
| Methysergide (Sansert®) | synthetic ergot / serotonin antagonist | methysergide | 2mg tablets. Side effects | |
| Indocin® | NSAID | indomethacin | capsules, suppositories. Can be hard on stomach | |
| Bellergal S® | vasoconstrictor / sedative | belladonna, ergotamine, phenobarbital | tablets | |
| Effexor® | tricyclic antidepressant | venlafaxine hydrochloride | tablets | |
| Elavil® | tricyclic antidepressant | amitriptyline | 10 - 150mg tablets | |
| Tegretol® | anticonvulsant | carbamazepine | ||
| Lamictal® | anticonvulsant | lamotrigine | ||
| Tenormin® | beta-blocker | atenolol | ||
| Inderal® | beta-blocker | propranolol | ||
| Amerge® | vasoconstrictor | naratriptan hydrocloride | 1mg, 2.5mg tablets. Taken at bedtime, may prevent the night cluster. | |
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Transitional Medications |
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| Prednisone | steroid | prednisone | side effects likely | |
| Dexamethasone | adrenalcorticosteroid | dexamethasone | ||
| DISCLAIMER: The use of brand names on this page is in no way a recommendation of one particular brand over another or over a generic equivalent. The information provided on this web site is for educational and informational purposes only. It should not be used as a substitute for seeking professional care or for the diagnosis and treatment of any medical disorder. O.U.C.H. makes no claims as to the scientific/clinical validity of the information on this site OR to that of the information linked to from this site. All information taken from the internet should be discussed with a medical professional! | ||||
Page Last Updated: 08/21/2008