Naratriptan

Cephalalgia. 2002 Dec;22(10):815-7.

Naratriptan in the preventive treatment of cluster headache.

Mulder LJ, Spierings EL.

Department of Neurology, Ikazia Hospital, Rotterdam, the Netherlands.

We describe the preventive use of naratriptan, mostly as add-on to high-dose verapamil treatment, in nine patients with cluster headache. The addition of the naratriptan further improved the headaches in seven of the nine patients.

PMID: 12485208

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Headache. 2002 Jan;42(1):56-7.

Naratriptan in the prophylaxis of cluster headache.

Loder E.

Harvard Medical School , Boston, Mass 02114, USA.

A 36-year-old man with cluster headache refractory to trials of standard prophylactic treatment and only partially responsive to parenteral sumatriptan and inhaled oxygen was admitted to an inpatient pain unit. The diagnosis of cluster headache was confirmed by direct observation of a typical attack. Despite efforts at prophylaxis, the patient continued to experience three to four severe headaches per day. Attempts to control his headaches with scheduled parenteral dihydroergotamine were successful, but headaches recurred when the medication was tapered, and continuous or intermittent use of parenteral dihydroergotamine was not felt to be a practical option for the patient. Naratriptan 2.5 mg twice daily completely abolished his headaches, which recurred when the medication was discontinued. No electrocardiographic or laboratory abnormalities were observed during treatment, and the patient reported no side effects.

PMID: 12005276

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Page Last Updated: 11/27/2007